There's only the briefest pause, wherein Obi-Wan softens, droops just a little, before taking Padmé's hand, giving her a smile that reflects how he feels more fully; sad, bittersweet, but thankful for her presence.

"They'll be all right." He means it won't hurt to let them sleep unaccompanied for a little while, but realizes after he's said it that he's also reassuring her about the future. He doesn't know it for certain, and shies away from any visions he has, but he believes that between the two of them, they can protect the children. At least until they're old enouh to protect themselves.